Diseases of the cardiovascular system are the most frequent cause of death a problem which will further increase due to aging demographics therefore approaches to tissue engineering and regenerative medicine that have the ability to reconstruct functional healthy cardiovascular structures could have a major impact on health care delivery. Noncardiac regenerative models although the focus of this article is cardiac models for the study of cardiac regeneration noncardiac animal models can provide clues to cardiac regenerative biology using methods that are less expensive or have fewer logistical or technical challenges. Basel o freiburg o paris o london o new york o new delhi o bangkok o beijing o tokyo o kuala lumpur o singapore o sydney cardiovascular. This special issue of cells tissues organs contains a collection of state of the art papers on cardiovascular regenerative medicineperiod diseases of the . Disease of the cardiovascular system accounts for nearly one million deaths per year in the usa alone and aging demographics mean that this problem will
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